Association between Body Mass Index and Vitamin D Serum in Asian Population: A Systematic Review
DOI:
https://doi.org/10.53638/phpma.2022.v10.i1.p08Keywords:
Vitamin D, body mass index, underweight, obesity, AsianAbstract
than other populations with the same body mass index (BMI). Fat accumulation is suspected of mediating the rise and fall of Vitamin D levels linked to BMI. However, the results of studies assessing the association between BMI and Vitamin D serum in Asian population still varied. This study is conducted to determine the association between BMI and vitamin D serum in the Asian population.
Methods: This study was conducted with a systematic review method to identify scientific articles reporting the association between BMI and Vitamin D serum in the Asian population. The data collected for this systematic review were from 5,477 studies filtered with the inclusion and exclusion criteria, resulting in eleven studies presenting 7,496 respondents.
Results: Nine studies concluded an association between increasing BMI from the normal range and decreasing Vitamin D serum (p<0,05). One study has concluded an association between decreasing BMI from the normal range and decreasing Vitamin D serum (p<0,05). Another has concluded there is no association between BMI and Vitamin D serum (p>0,05).
Conclusion:This systematic review study concludes an association between increasing and decreasing BMI with decreasing Vitamin D serum in the Asian population. Further study using clinical trial in obese people and control to compare the metabolism of Vitamin D should be conducted.
References
Amrein K, Scherkl M, Hoffmann M, Neuwersch-Sommeregger S, Köstenberger M, Tmava Berisha A, et al. Vitamin D deficiency 2.0: an update on the current status worldwide. European Journal of Clinical Nutrition. 2020; 74(11): 1498-1513.
Yan X, Zhang N, Cheng S, Wang Z, Qin Y. Gender differences in Vitamin D status in China. Medical Science Monitor. 2019; 25: 7094–7099.
Edwards MH, Cole ZA, Harvey NC, Cooper C. The global epidemiology of Vitamin D status. JARLIFE: The Journal of Aging Research and Lifetime. 2014; 3(3): 148-158.
Roth DE, Abrams SA, Aloia J, Bergeron G, Bourassa MW, Brown KH, et al. Global prevalence and disease burden of Vitamin D deficiency: a roadmap for action in low‐ and middle‐income countries. Annals of the New York Academy of Sciences. 2018 Oct; 1430(1): 44–79.
Man R, Li L-J, Cheng C-Y, Wong T, Lamoureux E, Sabanayagam C. Prevalence and determinants of suboptimal Vitamin D levels in a multiethnic Asian population. Nutrients. 2017 Mar 22; 9(3): 313.
Xie Z, Xia W, Zhang Z, Wu W, Lu C, Tao S, et al. Prevalence of Vitamin D inadequacy among Chinese postmenopausal women: a nationwide, multicenter, cross-sectional study. Frontiers in Endocrinology. 2019 Jan 7; 9: 782.
Aji AS, Erwinda E, Yusrawati Y, Malik SG, Lipoeto NI. Vitamin D deficiency status and its related risk factors during early pregnancy: a cross-sectional study of pregnant Minangkabau women, Indonesia. BMC Pregnancy and Childbirth. 2019; 19(1): 1–10.
Cipriani C, Pepe J, Piemonte S, Colangelo L, Cilli M, Minisola S. Vitamin D and its relationship with obesity and muscle. International Journal of Endocrinology. 2014 Oct; 14.
Zaidi S. Power of Vitamin D. Denver, Colorado: Outskirts Press; 2010.
Office of Dietary Supplements. Vitamin D [Internet]. 2020 (cited 2020 Aug 17). Available from: https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
Healio. Endocrine Society publishes clinical practice guidelines for Vitamin D deficiency [Internet]. 2020 (cited 2020 Oct 17). Available from: https://www.healio.com/news/endocrinology/20131127/endocrine-society-publishes-clinical-practice-guidelines-for-vitamin-d-deficiency
Shah D, Gupta P. Vitamin D deficiency: Is the pandemic for real? Indian Journal of Community Medicine. 2015 Oct; 40(4): 215.
Vanlint S. Vitamin D and obesity. Nutrients. 2013; 5(3): 949–956.
World Health Organization Europe. A healthy lifestyle - WHO recommendations [Internet]. 2020 (cited 2020 Jun 15). Available from: https://www.euro.who.int/en/health-topics/disease-prevention/nutrition/a-healthy-lifestyle/body-mass-index-bmi
World Health Organization. Noncommunicable diseases risk factors: Overweight/Obesity [Internet]. 2020 [cited 2020 May 29]. Available from: http://www.who.int/gho/ncd/risk_factors/overweight_text/en/
Anuurad E, Shiwaku K, Nogi A, Kitajima K, Enkhmaa B, Shimono K, et al. The new BMI criteria for Asians by the regional office for the western pacific region of WHO are suitable for screening of overweight to prevent metabolic syndrome in elder Japanese workers. Journal of Occupational Health. 2003; 45(6) :335–343.
Wang LK, Hung KC, Lin YT, Chang YJ, Wu ZF, Ho CH, et al. Age, gender and season are good predictors of vitamin D status independent of body mass index in office workers in a subtropical region. Nutrients. 2020 Sep 5; 12(9): 2719.
Modesti PA, Reboldi G, Cappuccio FP, Agyemang C, Remuzzi G, Rapi S, et al. Panethnic differences in blood pressure in Europe: a systematic review and meta-analysis. PloS one. 2016 Jan 25; 11(1): e0147601.
Ribeiro CM, Beserra BTS, Silva NG, Lima CL, Rocha PRS, Coelho MS, et al. Exposure to endocrine-disrupting chemicals and anthropometric measures of obesity: a systematic review and meta-analysis. BMJ Open. 2020 Jun; 10(6): e033509.
Hao Y, Ma X, Shen Y, Ni J, Luo Y, Xiao Y, et al. Associations of serum 25-Hydroxyvitamin D3 levels with visceral adipose tissue in Chinese men with normal glucose tolerance. Slominski AT, editor. PLoS One. 2014 Jan 22; 9(1): e86773.
Shafinaz IS, Moy FM. Vitamin D level and its association with adiposity among multi-ethnic adults in Kuala Lumpur, Malaysia: a cross sectional study. BMC Public Health. 2016 Dec; 16(1): 1-9.
Chiang JM, Stanczyk FZ, Kanaya AM. Vitamin D levels, body composition, and metabolic factors in Asian Indians: Results from the metabolic syndrome and atherosclerosis in South Asians living in America pilot study. Annals of Nutrition and Metabolism. 2018; 72(3): 223-230.
Yin X, Sun Q, Zhang X, Lu Y, Sun C, Cui Y, et al. Serum 25(OH)D is inversely associated with metabolic syndrome risk profile among urban middle-aged Chinese population. Nutrition Journal. 2012 Dec; 11(1): 1-7.
Kim KJ, Kim YJ, Kim SH, An JH, Yoo HJ, Kim HY, et al. Vitamin D status and associated metabolic risk factors among North Korean refugees in South Korea: a cross-sectional study. BMJ Open. 2015 Nov; 5(11): e009140.
Suryanarayana P, Arlappa N, Sai Santhosh V, Balakrishna N, Lakshmi Rajkumar P, Prasad U, et al. Prevalence of Vitamin D deficiency and its associated factors among the urban elderly population in Hyderabad metropolitan city, South India. Annals of Human Biology. 2018 Feb 17; 45(2): 133–139.
Moy FM, Bulgiba A. High prevalence of Vitamin D insufficiency and its association with obesity and metabolic syndrome among Malay adults in Kuala Lumpur, Malaysia. BMC Public Health. 2011 Dec; 11(1): 1-7.
Fatima SS, Farooq S, Tauni MA, Irfan O, Alam F. Effect of raised body fat on Vitamin D, leptin and bone mass. Journal of Pakistan Medical Association. 2015; 65(12): 1315.
Erkus E, Helvaci A, Adas M, Bilge M. Obesity is associated with lower levels of Vitamin D. Experimental Biomedical Research. 2018 May 7; 1(3): 82–89.
Alloubani A, Akhu-Zaheya L, Samara R, Abdulhafiz I, Saleh A, Altowijri A. Relationship between Vitamin D deficiency, diabetes, and obesity. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2019 Mar; 13(2): 1457–1461.
Forrest KY, Stuhldreher WL. Prevalence and correlates of Vitamin D deficiency in US adults. Nutrition Research. 2011 Jan; 31(1): 48–54.
Vranić L, Mikolašević I, Milić S. Vitamin D deficiency: consequence or cause of obesity? Medicina. 2019 Aug; 55(9): 541.
Joh HK, Lim CS, Cho B. Lifestyle and dietary factors associated with Serum 25-Hydroxyvitamin D levels in Korean young adults. Journal of Korean Medical Science. 2015 Aug; 30(8): 1110-1120.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Janice Suhartono, Yunisa Astiarani, Regina

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
**Creative Commons Attribution 4.0 International License (CC BY 4.0)**
*Welcome to the world of open collaboration and shared creativity! The Creative Commons Attribution 4.0 International License (CC BY 4.0) empowers creators to share their work with the world while maintaining certain rights.*
**Key Points:**
1. **Freedom to Share:** CC BY 4.0 allows creators to share their work globally, granting others the freedom to use, remix, and build upon it.
2. **Attribution Requirement:** Users can use the work for any purpose, even commercially, as long as they provide appropriate credit to the original creator.
3. **Flexibility:** Applicable to various content types—text, images, music, videos—the license fosters a diverse range of creations.
**Common Use Cases:**
- **Education:** Widely used for educational materials, promoting open learning environments.
- **Research:** Applied to scholarly articles, accelerating the dissemination of knowledge.
**How to Use:**
1. **Share:** Share your work with the world, marking it with the CC BY 4.0 license.
2. **Attribution:** Users, when utilizing the work, must provide proper attribution to honor the original creator.
**Conclusion:**
CC BY 4.0 contributes to a more open and collaborative digital landscape. Join the movement of shared knowledge and creativity!
*For full license details, visit [Creative Commons](https://creativecommons.org/licenses/by/4.0/).*
