Risk factors for hepatitis B virus infections among pregnant women in East Lombok District
DOI:
https://doi.org/10.53638/phpma.2018.v6.i2.p06Keywords:
Risk factors, hepatitis B infection, pregnant women, East LombokAbstract
Background and purpose: The World Health Organization (WHO) has set a target of 90% reduction in new hepatitis B infections by 2030. The WHO program includes prevention of new infections, and increases testing uptake and treatment. In order to effectively foster prevention, it is necessary to understand the risk factors for transmission. This study aims to determine the risk factors of hepatitis B infection in pregnant women.
Methods: A case control study was carried out among 52 pregnant women with HBsAg (+) as cases and 104 pregnant women with HBsAg (-) as controls. The source of cases and controls was the register of pregnant women at the Pringgasela Public Health Center from January 2016 to October 2017. Cases were selected using systematic random sampling from 67 HBsAg (+) pregnant women and controls were selected in the same way from 1644 pregnant women with HBsAg (-). Cases and controls were matched by domicile. The data collected were age, age of first marriage, education, family income, parity, history of miscarriage, maternal or husband’s history of working abroad, frequency of marriage, history of injection, surgery, blood transfusion and dental care. Data collection was carried out with a pre-tested questionnaire in April-May 2018 through interviews at the home of each respondent. Multivariate analysis with logistic regression was carried out to determine the adjusted odds ratio of each risk factor.
Results: Cases and controls characteristics were found to be similar in terms of age, domicile, education and income. Significant risk factors were the history of husband working abroad (AOR=4.28; 95%CI: 1.66- 11.08), age of first marriage ≤19 years (AOR=2.52; 95%CI: 1.16-5.48) and frequency of husband's marriage more than one time (AOR=3.08; 95%CI: 1.35-7.08).
Conclusion: Husbands with history of working abroad, age of first marriage <20 years and frequency of husband's marriage more than one time were found to be the risk factors for hepatitis B infection in pregnant women. These factors require public health attention in order to reduce the transmission of hepatitis B.
References
World Health Organization. Global Hepatitis Report. France; 2017.
World Health Organization. Hepatitis B. (serial online), [cited 2018 Feb. 06]. 2018. Available from: http://www.who.int/en/news-room/fact-sheets/detail/hepatitis-b.
Cahyono SB. Hepatitis B. 1st edition. Sri I, editor. Yogyakarta: Kanisius; 2010. 1-114.
Ministry of Health of Indonesia. 150 ribu orang potensial alami hepatitis kronis [150 thousands people potentially suffer from chronic hepatitis]. (serial online), [cited 2018 Sep. 07]. 2017. Available from: http://www.depkes.go.id/150-ribu-orang-potensialalami-hepatitis-kronis.html.
Pringgasela Public Health Center. Hasil pemeriksaan deteksi dini hepatitis B pada ibu hamil [Results of hepatitis B early detection among pregnant women]. Selong; 2016. Unpublished.
Anaedobe CG, Fowotade A, Omoruyi CE, Bakare RA. Prevalence, socio-demographic features and risk factors of hepatitis B virus infection among pregnant women in Southwestern Nigeria. The Pan African Medical Journal. 2015; 20(6206): 406.
Alrowaily MA, Abolfotouh MA, Ferwanah MS. Hepatitis B virus sero-prevalence among pregnant females in Saudia Arabia. The Saudi Journal of Gastroenterology. 2008; 14(2): 70–2.
Metaferia Y, Dessie W, Ali I, Amsalu A. Seroprevalence and associated risk factors of hepatitis B virus among pregnant women in Southern Ethiopia: a hospital-based crosssectional study. Epidemiology and Health. 2016; 38: 1–7.
Nwachukwu NC, Iheukwumere I, Onyekwere VO. Seroprevalence of hepatitis B surface antigens (HBsAg) among pregnant women attending antenatal in Unth, Ituku Ozalla, Nigeria. International Journal of Arts & Sciences. 2014; 7(3): 581.
Obi SN, Onah HE, Ezugwu FO. Risk factors for hepatitis B infection during pregnancy in a Nigerian obstetric population. Journal of Obstetrics and Gynaecology. 2006; 26(8): 770–2.
Onwere S, Chigbu B, Aluka C, Kamanu CI, Okoro O, P.E. Ndukwe C, et al. Risk factors for hepatitis B virus infection during pregnancy in South Eastern Nigeria. East African Medical Journal. 2012; 89(3): 89–93.
Umare A, Seyoum B, Gobena T, Mariyam TH. Hepatitis B virus infections and associated factors among pregnant women attending antenatal care clinic at Deder Hospital, Eastern Ethiopia. PLoS ONE. 2016; 11(11): 1–11.
Frambo AAB, Atashili J, Fon PN, Ndumbe PM. Prevalence of HBsAg and knowledge about hepatitis B in pregnancy in the Buea Health District, Cameroon: a cross-sectional study. BioMed Central Research Notes. 2014; 7(394): 1–7.
Omilabu MA, Okunade K, Gbadegesin A, Olowoselu O, Olowule A, Ombilabu S. Seroprevalence of hepatitis B virus infection among pregnant women at the antenatal booking clinic of a tertiary hospital in Lagos Nigeria. Nigerian Journal of Clinical Practice. 2015; 18(6): 819–23.
Rabiu KA, Akinola OI, Adewunmi AA, Omololu OM, Ojo TO. Risk factors for hepatitis B virus infection among pregnant women in Lagos, Nigeria. Acta Obstetricia et Gynecologica. 2010; 89(8): 1024–8.
Zenebe Y, Mulu W, Yimer M, Abera B. Sero-prevalence and risk factors of hepatitis B virus and human immunodeficiency virus infection among pregnant women in Bahir Dar City, Northwest Ethiopia: a cross sectional study. BioMed Central Infectious Diseases. 2014; 14(118): 1471–2334.
Li X, Zheng Y, Liau A, Cai B, Ye D, Huang F, et al. Hepatitis B virus infections and risk factors among the general population in Anhui Province, China: An epidemiological study. BioMed Central Public Health. 2012; 12(1): 272.
Amtarina R, Arfianti A, Zainal A, Chandra F. Faktor risiko hepatitis B pada tenaga kesehatan Kota Pekanbaru [Risk factors of hepatitis B among health workers in Pekanbaru City]. Majalah Kedokteran Bandung. 2009; 41(3): 1–7.
Aini R, Susiloningsih J. Faktor risiko yang berhubungan dengan kejadian hepatitis B pada Pondok Pesantren Putri Ibnul Qoyyim Yogyakarta [Risks factors associated with hepatitis B prevalence at Ibnul Qoyyim Female Islamic Boarding School Yogyakarta]. Sains Medika. 2013; 5(1): 30–3.
Merry V. Pengelolaan hepatitis B dalam kehamilan dan persalinan (Tesis) [Management of hepatitis B during pregnancy and labor (Thesis)]. Semarang: Universitas Diponegoro; 2001.
Pusparini AD, Ayu PR. Tatalaksana persalinan pada kehamilan dengan hepatitis B [Management of labor in pregnancy with hepatitis B]. Jurnal Medula Unila. 2017; 7(2): 1–5.
National Authority for the Placement and Protection of Indonesian Overseas Workers. Data penempatan dan perlindungan tenaga kerja Indonesia tahun 2015 [Data of placement and protection of Indonesian overseas workers 2015]. Jakarta Selatan: National Authority for the Placement and Protection of Indonesian Overseas Workers; 2015.
National Authority for the Placement and Protection of Indonesian Overseas Workers. Data penempatan dan perlindungan TKI periode Januari s.d Februari 2016 [Data of placement and protection of Indonesian overseas workers period of January-February 2016]. Jakarta Selatan: National Authority for the Placement and Protection of Indonesian Overseas Workers; 2016.
Statistics Office of East Lombok District. Kabupaten Lombok Timur dalam Angka 2017 [2017 East Lombok District in Number]. Selong: Statistics Office of East Lombok District; 2017
National Demographic and Family Planning Board. Survei Demografi dan Kesehatan Indonesia Tahun 2017 [The 2017 Indonesia Demographic and Health Survey]. Jakarta: National Demographic and Family Planning Board; 2018.
South Australian Maternal & Neonatal Community of Practice. Clinical guideline hepatitis B in pregnancy. Australia; 2016.
Kandun IN. Manual pemberantasan penyakit menular [Manual of infectious diseases control]. 17th edition. Chin J, editor. Jakarta; 2000.
Marschall T, Krämer A, Prüfer-Krämer L, Mikolajczyk R, Kretzschmar M. Erhöhen migrationen aus hohen und mittleren endemiegebieten die hepatitis B-prävalenz in Deutschland?. Deutsche Medizinische Wochenschrift. 2005; 130(48): 2753–8.
Zhang L, Wang Y, Huang Y, Wang Q, Nelson KE, Wang A, et al. Status of HBsAg seroprevalence in 15 million rural couples in China: a cross-sectional study. Scientific Reports. 2017; 42822(7): 1–7.
United Nations Children’s Fund. Ending child marriage progress and prospects. New York; 2014.
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